Role of vascular calcification inhibitors in preventing vascular dysfunction and mortality in hemodialysis patients.
Semin Dial
; 31(1): 72-81, 2018 01.
Article
en En
| MEDLINE
| ID: mdl-28608927
ABSTRACT
Cardiovascular events make up the primary cause of death in hemodialysis patients, and the risk for cardiovascular mortality is significantly increased by vascular calcification, a condition observed frequently in this patient population. The mechanisms underlying the pathogenesis of vascular calcification are complex, and many factors facilitate or hinder the development of calcification. In this review, we first summarize the main factors contributing to the pathogenesis of vascular calcification in patients with end-stage renal disease. We then explore the role of calcification inhibitors in the calcification process, as well as their effect on vascular dysfunction and mortality in hemodialysis patients.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades Cardiovasculares
/
Causas de Muerte
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Diálisis Renal
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Calcificación Vascular
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Fallo Renal Crónico
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
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Observational_studies
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Prognostic_studies
/
Risk_factors_studies
Límite:
Female
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Humans
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Male
Idioma:
En
Año:
2018
Tipo del documento:
Article