1,25-dihydroxyvitamin D<sub>3</sub> -induced dendritic cells suppress experimental autoimmune encephalomyelitis by increasing proportions of the regulatory lymphocytes and reducing T helper type 1 and type 17 cells.

Xie, Zhongxiang; Chen, Jingtao; Zheng, Chao; Wu, Jing; Cheng, Yun; Zhu, Shan; Lin, Chenhong; Cao, Qingqing; Zhu, Jie; Jin, Tao

1,25-dihydroxyvitamin D₃ -induced dendritic cells suppress experimental autoimmune encephalomyelitis by increasing proportions of the regulatory lymphocytes and reducing T helper type 1 and type 17 cells.

Xie, Zhongxiang; Chen, Jingtao; Zheng, Chao; Wu, Jing; Cheng, Yun; Zhu, Shan; Lin, Chenhong; Cao, Qingqing; Zhu, Jie; Jin, Tao.

Xie Z; Department of Neurology and Neuroscience Centre, The First Hospital of Jilin University, Changchun, China.
Chen J; Institute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Zheng C; Department of Neurology and Neuroscience Centre, The First Hospital of Jilin University, Changchun, China.
Wu J; Institute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Cheng Y; Department of Neurology and Neuroscience Centre, The First Hospital of Jilin University, Changchun, China.
Zhu S; Institute of Translational Medicine, The First Hospital of Jilin University, Changchun, China.
Lin C; Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
Cao Q; Department of Neurology and Neuroscience Centre, The First Hospital of Jilin University, Changchun, China.
Zhu J; Department of Neurology and Neuroscience Centre, The First Hospital of Jilin University, Changchun, China.
Jin T; Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.

Immunology ; 152(3): 414-424, 2017 11.

Article en En | MEDLINE | ID: mdl-28617989

Asunto(s)

Traslado Adoptivo; Células Dendríticas/efectos de los fármacos; Células Dendríticas/trasplante; Encefalomielitis Autoinmune Experimental/terapia; Ergocalciferoles/farmacología; Tolerancia Inmunológica/efectos de los fármacos; Factores Inmunológicos/farmacología; Médula Espinal/inmunología; Linfocitos T Reguladores/inmunología; Células TH1/inmunología; Células Th17/inmunología; Animales; Linfocitos B Reguladores/inmunología; Linfocitos B Reguladores/metabolismo; Células Cultivadas; Quimiotaxis de Leucocito; Células Dendríticas/inmunología; Células Dendríticas/metabolismo; Encefalomielitis Autoinmune Experimental/sangre; Encefalomielitis Autoinmune Experimental/inmunología; Femenino; Inmunoglobulina G/sangre; Interleucina-10/sangre; Interleucina-10/inmunología; Ganglios Linfáticos/inmunología; Ganglios Linfáticos/metabolismo; Ratones Endogámicos C57BL; Médula Espinal/metabolismo; Bazo/inmunología; Bazo/metabolismo; Linfocitos T Reguladores/metabolismo; Células TH1/metabolismo; Células Th17/metabolismo; Factores de Tiempo; Factor de Necrosis Tumoral alfa/sangre; Factor de Necrosis Tumoral alfa/inmunología

Palabras clave

1,25-dihydroxyvitamin D3; experimental autoimmune encephalomyelitis; multiple sclerosis; tolerogenic dendritic cells

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Médula Espinal / Células Dendríticas / Ergocalciferoles / Linfocitos T Reguladores / Células TH1 / Traslado Adoptivo / Encefalomielitis Autoinmune Experimental / Células Th17 / Tolerancia Inmunológica / Factores Inmunológicos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Año: 2017 Tipo del documento: Article

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