SnapShot: Phosphoregulation of Mitosis.
Cell
; 169(7): 1358-1358.e1, 2017 Jun 15.
Article
en En
| MEDLINE
| ID: mdl-28622516
ABSTRACT
During mitosis, a cell divides its duplicated genome into two identical daughter cells. This process must occur without errors to prevent proliferative diseases (e.g., cancer). A key mechanism controlling mitosis is the precise timing of more than 32,000 phosphorylation and dephosphorylation events by a network of kinases and counterbalancing phosphatases. The identity, magnitude, and temporal regulation of these events have emerged recently, largely from advances in mass spectrometry. Here, we show phosphoevents currently believed to be key regulators of mitosis. For an animated version of this SnapShot, please see http//www.cell.com/cell/enhanced/odonoghue2.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Proteínas Quinasas
/
Mitosis
Límite:
Animals
/
Humans
Idioma:
En
Año:
2017
Tipo del documento:
Article