Settling the m<sup>6</sup>A debate: methylation of mature mRNA is not dynamic but accelerates turnover.

Rosa-Mercado, Nicolle A; Withers, Johanna B; Steitz, Joan A

Settling the m⁶A debate: methylation of mature mRNA is not dynamic but accelerates turnover.

Rosa-Mercado, Nicolle A; Withers, Johanna B; Steitz, Joan A.

Rosa-Mercado NA; Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06536, USA.
Withers JB; Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06536, USA.
Steitz JA; Department of Molecular Biophysics and Biochemistry, Boyer Center for Molecular Medicine, Yale University School of Medicine, New Haven, Connecticut 06536, USA.

Genes Dev ; 31(10): 957-958, 2017 05 15.

Article en En | MEDLINE | ID: mdl-28637691

Asunto(s)

Adenosina/metabolismo; Empalme del ARN/fisiología; ARN Mensajero/metabolismo; Adenosina/análisis; Animales; Exones/genética; Células HeLa; Humanos; Metilación; Metiltransferasas/metabolismo

Palabras clave

cell fractionation; m6A-CLIP; mRNA turnover; pre-mRNA

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Mensajero / Adenosina / Empalme del ARN Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google