Designing structural-motifs for the preparation of acylated proinsulin and their regiospecific conversion into insulin modified at Lys<sup>29</sup> (K<sup>29</sup>).

Ahmad, Munir; Gardner, QurratulAnn Afza; Rashid, Naeem; Akhtar, Muhammad

Designing structural-motifs for the preparation of acylated proinsulin and their regiospecific conversion into insulin modified at Lys²⁹ (K²⁹).

Ahmad, Munir; Gardner, QurratulAnn Afza; Rashid, Naeem; Akhtar, Muhammad.

Ahmad M; School of Biological Sciences, University of the Punjab, New Campus, Lahore 54590, Pakistan.
Gardner QA; School of Biological Sciences, University of the Punjab, New Campus, Lahore 54590, Pakistan. Electronic address: annegardner80@yahoo.co.uk.
Rashid N; School of Biological Sciences, University of the Punjab, New Campus, Lahore 54590, Pakistan.
Akhtar M; School of Biological Sciences, University of the Punjab, New Campus, Lahore 54590, Pakistan; Biological Sciences, University of Southampton, SO17 1BJ, UK. Electronic address: ma3@soton.ac.uk.

Bioorg Chem ; 73: 147-153, 2017 08.

Article en En | MEDLINE | ID: mdl-28672221

Asunto(s)

Diseño de Fármacos; Insulina/síntesis química; Lisina/química; Proinsulina/química; Humanos; Insulina/química; Estereoisomerismo

Palabras clave

Acetyl insulin; Acetyl proinsulin; Carboxypeptidase B unusual specificity; Dodecanoyl insulin; Dodecanoyl proinsulin; Lauryl insulin; Lauryl proinsulin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proinsulina / Diseño de Fármacos / Insulina / Lisina Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article

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