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An immunogenic personal neoantigen vaccine for patients with melanoma.
Ott, Patrick A; Hu, Zhuting; Keskin, Derin B; Shukla, Sachet A; Sun, Jing; Bozym, David J; Zhang, Wandi; Luoma, Adrienne; Giobbie-Hurder, Anita; Peter, Lauren; Chen, Christina; Olive, Oriol; Carter, Todd A; Li, Shuqiang; Lieb, David J; Eisenhaure, Thomas; Gjini, Evisa; Stevens, Jonathan; Lane, William J; Javeri, Indu; Nellaiappan, Kaliappanadar; Salazar, Andres M; Daley, Heather; Seaman, Michael; Buchbinder, Elizabeth I; Yoon, Charles H; Harden, Maegan; Lennon, Niall; Gabriel, Stacey; Rodig, Scott J; Barouch, Dan H; Aster, Jon C; Getz, Gad; Wucherpfennig, Kai; Neuberg, Donna; Ritz, Jerome; Lander, Eric S; Fritsch, Edward F; Hacohen, Nir; Wu, Catherine J.
  • Ott PA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Hu Z; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.
  • Keskin DB; Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Shukla SA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Sun J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Bozym DJ; Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Zhang W; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Luoma A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Giobbie-Hurder A; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Peter L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Chen C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Olive O; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Carter TA; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Li S; Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Lieb DJ; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.
  • Eisenhaure T; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts 02139, USA.
  • Gjini E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Stevens J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Lane WJ; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Javeri I; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Nellaiappan K; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Salazar AM; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Daley H; Center for Immuno-Oncology (CIO), Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Seaman M; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.
  • Buchbinder EI; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.
  • Yoon CH; CuriRx, Inc., Wilmington, Massachusetts 01887, USA.
  • Harden M; CuriRx, Inc., Wilmington, Massachusetts 01887, USA.
  • Lennon N; Oncovir, Inc., 3203 Cleveland Avenue, NW, Washington DC 20008, USA.
  • Gabriel S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Rodig SJ; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.
  • Barouch DH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Aster JC; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.
  • Getz G; Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Wucherpfennig K; Harvard Medical School, Boston, Massachusetts 02215, USA.
  • Neuberg D; Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.
  • Ritz J; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Lander ES; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Fritsch EF; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.
  • Hacohen N; Center for Immuno-Oncology (CIO), Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.
  • Wu CJ; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts 02215, USA.
Nature ; 547(7662): 217-221, 2017 07 13.
Article en En | MEDLINE | ID: mdl-28678778
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas contra el Cáncer / Medicina de Precisión / Melanoma / Antígenos de Neoplasias Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Vacunas contra el Cáncer / Medicina de Precisión / Melanoma / Antígenos de Neoplasias Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article