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First dual AK/GSK-3ß inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents.
Brogi, Simone; Ramunno, Anna; Savi, Lida; Chemi, Giulia; Alfano, Gloria; Pecorelli, Alessandra; Pambianchi, Erika; Galatello, Paola; Compagnoni, Giulia; Focher, Federico; Biamonti, Giuseppe; Valacchi, Giuseppe; Butini, Stefania; Gemma, Sandra; Campiani, Giuseppe; Brindisi, Margherita.
  • Brogi S; European Research Centre for Drug Discovery and Development (NatSynDrugs), Department of Biotechnology, Chemistry, and Pharmacy, Università degli Studi di Siena via Aldo Moro 2, 53100 Siena, Italy.
  • Ramunno A; Dipartimento di Farmacia/DIFARMA, Università degli Studi di Salerno, via Giovanni Paolo II 132, 84084 Fisciano, Salerno, Italy.
  • Savi L; Istituto di Genetica Molecolare, CNR, via Abbiategrasso 207, 27100 Pavia, Italy.
  • Chemi G; European Research Centre for Drug Discovery and Development (NatSynDrugs), Department of Biotechnology, Chemistry, and Pharmacy, Università degli Studi di Siena via Aldo Moro 2, 53100 Siena, Italy.
  • Alfano G; European Research Centre for Drug Discovery and Development (NatSynDrugs), Department of Biotechnology, Chemistry, and Pharmacy, Università degli Studi di Siena via Aldo Moro 2, 53100 Siena, Italy.
  • Pecorelli A; Department of Animal Science, North Carolina State University, NC Research Campus, PHHI Building, 600 Laureate Way, Kannapolis 28081, NC USA.
  • Pambianchi E; Department of Animal Science, North Carolina State University, NC Research Campus, PHHI Building, 600 Laureate Way, Kannapolis 28081, NC USA.
  • Galatello P; Dipartimento di Farmacia/DIFARMA, Università degli Studi di Salerno, via Giovanni Paolo II 132, 84084 Fisciano, Salerno, Italy.
  • Compagnoni G; Istituto di Genetica Molecolare, CNR, via Abbiategrasso 207, 27100 Pavia, Italy.
  • Focher F; Istituto di Genetica Molecolare, CNR, via Abbiategrasso 207, 27100 Pavia, Italy. Electronic address: focher@igm.cnr.it.
  • Biamonti G; Istituto di Genetica Molecolare, CNR, via Abbiategrasso 207, 27100 Pavia, Italy.
  • Valacchi G; Department of Animal Science, North Carolina State University, NC Research Campus, PHHI Building, 600 Laureate Way, Kannapolis 28081, NC USA; Department of Life Sciences and Biotechnology, University of Ferrara, Via Borsari 46, 441212, Ferrara, Italy.
  • Butini S; European Research Centre for Drug Discovery and Development (NatSynDrugs), Department of Biotechnology, Chemistry, and Pharmacy, Università degli Studi di Siena via Aldo Moro 2, 53100 Siena, Italy. Electronic address: butini3@unisi.it.
  • Gemma S; European Research Centre for Drug Discovery and Development (NatSynDrugs), Department of Biotechnology, Chemistry, and Pharmacy, Università degli Studi di Siena via Aldo Moro 2, 53100 Siena, Italy. Electronic address: gemma@unisi.it.
  • Campiani G; European Research Centre for Drug Discovery and Development (NatSynDrugs), Department of Biotechnology, Chemistry, and Pharmacy, Università degli Studi di Siena via Aldo Moro 2, 53100 Siena, Italy.
  • Brindisi M; European Research Centre for Drug Discovery and Development (NatSynDrugs), Department of Biotechnology, Chemistry, and Pharmacy, Università degli Studi di Siena via Aldo Moro 2, 53100 Siena, Italy.
Eur J Med Chem ; 138: 438-457, 2017 Sep 29.
Article en En | MEDLINE | ID: mdl-28689095
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Adenosina Quinasa / Fármacos Neuroprotectores / Inhibidores de Proteínas Quinasas / Glucógeno Sintasa Quinasa 3 beta / Neuroblastoma / Antioxidantes Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Adenosina Quinasa / Fármacos Neuroprotectores / Inhibidores de Proteínas Quinasas / Glucógeno Sintasa Quinasa 3 beta / Neuroblastoma / Antioxidantes Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article