Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasiveness.

Bugge, Marit; Bergstrom, Bjarte; Eide, Oda K; Solli, Helene; Kjønstad, Ingrid F; Stenvik, Jørgen; Espevik, Terje; Nilsen, Nadra J

Bugge, Marit; Bergstrom, Bjarte; Eide, Oda K; Solli, Helene; Kjønstad, Ingrid F; Stenvik, Jørgen; Espevik, Terje; Nilsen, Nadra J.

Bugge M; From the Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, 7489 Trondheim, Norway and.
Bergstrom B; the Clinic of Medicine, St. Olav's University Hospital, 7030 Trondheim, Norway.
Eide OK; From the Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, 7489 Trondheim, Norway and.
Solli H; From the Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, 7489 Trondheim, Norway and.
Kjønstad IF; From the Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, 7489 Trondheim, Norway and.
Stenvik J; From the Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, 7489 Trondheim, Norway and.
Espevik T; From the Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, 7489 Trondheim, Norway and.
Nilsen NJ; From the Centre of Molecular Inflammation Research, Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, 7489 Trondheim, Norway and.

J Biol Chem ; 292(37): 15408-15425, 2017 09 15.

Article en En | MEDLINE | ID: mdl-28717003

Asunto(s)

Quimiocina CXCL10/agonistas; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Mucosa Intestinal/metabolismo; Neoplasias Intestinales/metabolismo; Proteínas de Neoplasias/agonistas; Receptor Toll-Like 3/agonistas; Antineoplásicos/farmacología; Apoptosis/efectos de los fármacos; Proteínas Portadoras/toxicidad; Línea Celular; Línea Celular Tumoral; Quimiocina CXCL10/genética; Quimiocina CXCL10/metabolismo; Citocinas/agonistas; Citocinas/genética; Citocinas/metabolismo; Endocitosis/efectos de los fármacos; Humanos; Mucosa Intestinal/efectos de los fármacos; Mucosa Intestinal/inmunología; Mucosa Intestinal/patología; Neoplasias Intestinales/tratamiento farmacológico; Neoplasias Intestinales/inmunología; Neoplasias Intestinales/patología; Ligandos; Lipopolisacáridos/toxicidad; Invasividad Neoplásica/inmunología; Invasividad Neoplásica/patología; Invasividad Neoplásica/prevención & control; Proteínas de Neoplasias/antagonistas & inhibidores; Proteínas de Neoplasias/genética; Proteínas de Neoplasias/metabolismo; Poli I-C; Polinucleótidos/toxicidad; Regiones Promotoras Genéticas/efectos de los fármacos; Transporte de Proteínas/efectos de los fármacos; Proteolisis/efectos de los fármacos; Interferencia de ARN; Receptor Toll-Like 3/antagonistas & inhibidores; Receptor Toll-Like 3/genética; Receptor Toll-Like 3/metabolismo

Palabras clave

CXCL10/interferon Î³-induced protein 10 (IP-10); Toll-like receptor (TLR); cancer biology; cell surface; double-stranded RNA (dsRNA); innate immunity; interferon; intestinal epithelium; metastasis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Receptor Toll-Like 3 / Quimiocina CXCL10 / Mucosa Intestinal / Neoplasias Intestinales / Proteínas de Neoplasias Idioma: En Año: 2017 Tipo del documento: Article

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