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Long-term efficient control of SIV infection in macaques is associated with an intact intestinal barrier.
Daskalaki, Maria; Neumann, Berit; Klippert, Antonina; Mätz-Rensing, Kerstin; Kaup, Franz-Josef; Stahl-Hennig, Christiane.
  • Daskalaki M; Unit of Infection Models, Leibniz Institute for Primate Research, German Primate Center, Goettingen, Germany.
  • Neumann B; Unit of Infection Models, Leibniz Institute for Primate Research, German Primate Center, Goettingen, Germany.
  • Klippert A; Unit of Infection Models, Leibniz Institute for Primate Research, German Primate Center, Goettingen, Germany.
  • Mätz-Rensing K; Unit of Infection Pathology, Leibniz Institute for Primate Research, German Primate Center, Goettingen, Germany.
  • Kaup FJ; Unit of Infection Pathology, Leibniz Institute for Primate Research, German Primate Center, Goettingen, Germany.
  • Stahl-Hennig C; Unit of Infection Models, Leibniz Institute for Primate Research, German Primate Center, Goettingen, Germany.
J Med Primatol ; 46(4): 144-148, 2017 08.
Article en En | MEDLINE | ID: mdl-28748664
ABSTRACT
Hallmarks of SIV infection are early depletion of gut CD4 T cells and diminished intestinal integrity. Comprehensive studies on colon biopsies of SIV-infected macaques efficiently controlling infection revealed that in contrast to viremic and failing controllers, elite controllers show preserved CD4 T cells, and low viral load, apoptosis, and inflammation.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Síndrome de Inmunodeficiencia Adquirida del Simio / Colon / Macaca mulatta Tipo de estudio: Risk_factors_studies Límite: Animals País como asunto: Asia Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Síndrome de Inmunodeficiencia Adquirida del Simio / Colon / Macaca mulatta Tipo de estudio: Risk_factors_studies Límite: Animals País como asunto: Asia Idioma: En Año: 2017 Tipo del documento: Article