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Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites.
Rodríguez-Cortez, Virginia C; Martínez-Redondo, Paloma; Català-Moll, Francesc; Rodríguez-Ubreva, Javier; Garcia-Gomez, Antonio; Poorani-Subramani, Ganesh; Ciudad, Laura; Hernando, Henar; Pérez-García, Arantxa; Company, Carlos; Urquiza, José M; Ramiro, Almudena R; Di Noia, Javier M; Vaquero, Alejandro; Ballestar, Esteban.
  • Rodríguez-Cortez VC; Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Martínez-Redondo P; Chromatin Biology Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Català-Moll F; Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Rodríguez-Ubreva J; Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Garcia-Gomez A; Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Poorani-Subramani G; Institut de Recherches Cliniques de Montréal, Division of Immunity and Viral Infections, Montréal, H2W 1R7, Québec, Canada.
  • Ciudad L; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, QC, Canada.
  • Hernando H; Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Pérez-García A; Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Company C; B Cell Biology Lab, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.
  • Urquiza JM; Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Ramiro AR; Chromatin and Disease Group, Cancer Epigenetics and Biology Programme (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), 08908, L'Hospitalet de Llobregat, Barcelona, Spain.
  • Di Noia JM; B Cell Biology Lab, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.
  • Vaquero A; Institut de Recherches Cliniques de Montréal, Division of Immunity and Viral Infections, Montréal, H2W 1R7, Québec, Canada.
  • Ballestar E; Division of Experimental Medicine, Faculty of Medicine, McGill University, Montreal, QC, Canada.
Sci Rep ; 7(1): 7594, 2017 08 08.
Article en En | MEDLINE | ID: mdl-28790320
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Histonas / N-Metiltransferasa de Histona-Lisina / Cambio de Clase de Inmunoglobulina / Citidina Desaminasa / Epigénesis Genética / Síndrome de Inmunodeficiencia con Hiper-IgM Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Histonas / N-Metiltransferasa de Histona-Lisina / Cambio de Clase de Inmunoglobulina / Citidina Desaminasa / Epigénesis Genética / Síndrome de Inmunodeficiencia con Hiper-IgM Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article