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The selective PI3Kα inhibitor BYL719 as a novel therapeutic option for neuroendocrine tumors: Results from multiple cell line models.
Nölting, Svenja; Rentsch, Jakob; Freitag, Helma; Detjen, Katharina; Briest, Franziska; Möbs, Markus; Weissmann, Victoria; Siegmund, Britta; Auernhammer, Christoph J; Aristizabal Prada, Elke Tatjana; Lauseker, Michael; Grossman, Ashley; Exner, Samantha; Fischer, Christian; Grötzinger, Carsten; Schrader, Jörg; Grabowski, Patricia.
  • Nölting S; Department of Internal Medicine II, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany.
  • Rentsch J; Department of Internal Medicine IV, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany.
  • Freitag H; Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Detjen K; Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Briest F; Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Möbs M; Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Weissmann V; Dept. of Gastroenterology and Endocrinology, Zentralklinik Bad Berka GmbH, Bad Berka, Germany.
  • Siegmund B; Dept. of Chemistry and Biochemistry, Freie Universität (FU) Berlin, Berlin, Germany.
  • Auernhammer CJ; Institute of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Aristizabal Prada ET; Department of General, Visceral and Thoracic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Lauseker M; Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany.
  • Grossman A; Department of Internal Medicine II, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany.
  • Exner S; Department of Internal Medicine IV, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany.
  • Fischer C; Department of Internal Medicine II, Klinikum der Universität München (KUM), Ludwig-Maximilians-Universität München, München, Bavaria, Germany.
  • Grötzinger C; Institute for Medical Information Sciences, Biometry, and Epidemiology, Ludwig-Maximilians-Universität München, München, Bavaria, Germany.
  • Schrader J; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom and Neuroendocrine Tumour Centre, Royal Free Hospital, London, United Kingdom.
  • Grabowski P; Dept. of Gastroenterology, CC13 (CBF and CVK), Charité - Universitätsmedizin Berlin, Berlin, Germany.
PLoS One ; 12(8): e0182852, 2017.
Article en En | MEDLINE | ID: mdl-28800359
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Páncreas / Tiazoles / Regulación Neoplásica de la Expresión Génica / Inhibidores de Proteínas Quinasas / Fosfatidilinositol 3-Quinasa Clase I / Everolimus / Antineoplásicos Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Páncreas / Tiazoles / Regulación Neoplásica de la Expresión Génica / Inhibidores de Proteínas Quinasas / Fosfatidilinositol 3-Quinasa Clase I / Everolimus / Antineoplásicos Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article