In Vitro Fertilization Success Rates after Surgically Treated Endometriosis and Effect of Time Interval between Surgery and In Vitro Fertilization.
J Minim Invasive Gynecol
; 25(1): 99-104, 2018 01.
Article
en En
| MEDLINE
| ID: mdl-28807807
ABSTRACT
STUDY OBJECTIVE:
To evaluate the impact of endometriosis staging and endometriomas on in vitro fertilization (IVF) outcome and to assess the optimal time interval between laparoscopy and IVF.DESIGN:
A retrospective clinical study (Canadian Task Force classification II1).SETTING:
A university-affiliated private infertility clinic. PATIENTS Two hundred sixteen infertile patients with endometriosis and 209 infertile patients without endometriosis.INTERVENTIONS:
Laparoscopy, IVF. MEASUREMENTS AND MAINRESULTS:
Patients with endometriosis were classified according to American Society for Reproductive Medicine criteria; 58, 67, 63, and 28 patients had stages 1 through 4 disease, respectively. Patients with endometriosis had significantly lower estradiol on trigger day (9986 ± 6710 vs 12 220 ± 9414 pg/mL, respectively) and number of retrieved oocytes (12.7 ± 8.6 vs 14.0 ± 10, respectively) compared with controls. We found a consistent decline in clinical and ongoing pregnancy rates with increasing stage of endometriosis. The presence of endometrioma in patients with stages 3 and 4 endometriosis did not alter IVF outcome. Patients with a time interval of 7 to 12 and 13 to 25 months after surgery had a favorable outcome.CONCLUSION:
IVF pregnancy rate was negatively correlated with endometriosis severity. The presence of endometriomas had no impact on IVF clinical outcome. The optimal time to perform IVF appears to be between 7 and 25 months after endometriosis surgery.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades Uterinas
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Fertilización In Vitro
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Índice de Embarazo
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Endometriosis
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Infertilidad Femenina
Tipo de estudio:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Pregnancy
Idioma:
En
Año:
2018
Tipo del documento:
Article