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Health-related quality of life for everolimus versus placebo in patients with advanced, non-functional, well-differentiated gastrointestinal or lung neuroendocrine tumours (RADIANT-4): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
Pavel, Marianne E; Singh, Simron; Strosberg, Jonathan R; Bubuteishvili-Pacaud, Lida; Degtyarev, Evgeny; Neary, Maureen P; Carnaghi, Carlo; Tomasek, Jiri; Wolin, Edward; Raderer, Markus; Lahner, Harald; Valle, Juan W; Pommier, Rodney; Van Cutsem, Eric; Tesselaar, Margot E T; Fave, Gianfranco Delle; Buzzoni, Roberto; Hunger, Matthias; Eriksson, Jennifer; Cella, David; Ricci, Jean-François; Fazio, Nicola; Kulke, Matthew H; Yao, James C.
  • Pavel ME; Department of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany; Department of Medicine 1, Division of Endocrinology, Universitätsklinikum Erlangen, Erlangen, Germany.
  • Singh S; Division of Medical Oncology & Hematology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. Electronic address: simron.singh@sunnybrook.ca.
  • Strosberg JR; Department of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL, USA.
  • Bubuteishvili-Pacaud L; Novartis Pharma AG, Basel, Switzerland.
  • Degtyarev E; Novartis Pharma AG, Basel, Switzerland.
  • Neary MP; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA.
  • Carnaghi C; Oncology Unit, Humanitas Clinical and Research Centre, Rozzano, Italy.
  • Tomasek J; Clinic of Comprehensive Cancer Care, Masaryk Memorial Cancer Institute, Faculty of Medicine, Masaryk University, Brno, Czech Republic.
  • Wolin E; Department of Medical Oncology, Montefiore Einstein Center for Cancer Care, Bronx, NY, USA.
  • Raderer M; Department of Internal Medicine I, Division of Oncology, Klinik f Innere Medizin I, AKH, Vienna, Austria.
  • Lahner H; Klinik für Endokrinologie und Stoffwechselerkrankungen, Universitaetsklinikum Essen, Zentrum f Innere Medizin, Essen, Germany.
  • Valle JW; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
  • Pommier R; Division of Surgical Oncology, Oregon Health & Science University, Portland, OR, USA.
  • Van Cutsem E; University Hospitals Leuven, and KU Leuven, Digestive Oncology, Leuven, Belgium.
  • Tesselaar MET; Department of Medical Oncology, Antoni van Leeuwenhoek, Amsterdam, Netherlands.
  • Fave GD; Medical-Surgical Sciences and Translational Medicine, Azienda Ospedaliera Sant'Andrea - Università La Sapienza, Rome, Italy.
  • Buzzoni R; S C Day Hospital e Terapia Ambulatoriale Oncologica, Fondazione IRCCS - Istituto Nazionale dei Tumori, Milan, Italy.
  • Hunger M; Mapi, Munich, Germany.
  • Eriksson J; Mapi, Stockholm, Sweden.
  • Cella D; Department of Medical Social Sciences, Northwestern University, Chicago, IL, USA.
  • Ricci JF; Wellmera AG, Basel, Switzerland.
  • Fazio N; Unit of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, Milan, Italy.
  • Kulke MH; Medical Oncology and Solid Tumor Oncology, Dana Farber Cancer Institute, Boston, MA, USA.
  • Yao JC; Department of Gastrointestinal Medical Oncology, Division of Cancer Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Lancet Oncol ; 18(10): 1411-1422, 2017 10.
Article en En | MEDLINE | ID: mdl-28838862
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Calidad de Vida / Tumores Neuroendocrinos / Everolimus / Neoplasias Gastrointestinales / Neoplasias Pulmonares Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Calidad de Vida / Tumores Neuroendocrinos / Everolimus / Neoplasias Gastrointestinales / Neoplasias Pulmonares Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2017 Tipo del documento: Article