Levobunolol and metipranolol: comparative ocular hypotensive efficacy, safety, and comfort.
Br J Ophthalmol
; 71(4): 250-3, 1987 Apr.
Article
en En
| MEDLINE
| ID: mdl-2883990
ABSTRACT
Topical levobunolol 0.5% was compared with topical metipranolol 0.6% for efficacy, safety, and comfort in 46 patients with open angle glaucoma or ocular hypertension. The study was of parallel design, randomised, double-masked, and of three months' duration. After a washout interval the study medications were instilled twice daily in both eyes. The overall mean decrease in intraocular pressure (IOP) was approximately 7 mmHg in both groups. More than 90% of patients in both groups successfully completed the study. Both agents caused slight decreases in heart rate and blood pressure. More complaints of burning and stinging were reported in the metipranolol group than in the levobunolol group. This three-month, 46-patient study showed levobunolol 0.5% and metipranolol 0.6% to be similarly effective ocular hypotensive agents.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Propanolaminas
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Metipranolol
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Glaucoma de Ángulo Abierto
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Hipertensión Ocular
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Levobunolol
Tipo de estudio:
Clinical_trials
Límite:
Adult
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Aged
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Humans
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Middle aged
Idioma:
En
Año:
1987
Tipo del documento:
Article