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Inhibiting heat shock protein 90 and the ubiquitin-proteasome pathway impairs metabolic homeostasis and leads to cell death in human pancreatic cancer cells.
Belalcazar, Astrid; Shaib, Walid L; Farren, Matthew R; Zhang, Chao; Chen, Zhengjia; Yang, Lily; Lesinski, Gregory B; El-Rayes, Bassel F; Nagaraju, Ganji Purnachandra.
  • Belalcazar A; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • Shaib WL; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • Farren MR; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • Zhang C; Biostatistics and Bioinformatics, Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • Chen Z; Biostatistics and Bioinformatics, Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • Yang L; Surgery, Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • Lesinski GB; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • El-Rayes BF; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
  • Nagaraju GP; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia.
Cancer ; 123(24): 4924-4933, 2017 Dec 15.
Article en En | MEDLINE | ID: mdl-28841232

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Ubiquitinas / Adenocarcinoma / Proteínas HSP90 de Choque Térmico / Inhibidores de Proteasoma Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Ubiquitinas / Adenocarcinoma / Proteínas HSP90 de Choque Térmico / Inhibidores de Proteasoma Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article