[Effect of D-cellobiose on oral bioavailability of gentiopicroside].
Zhongguo Zhong Yao Za Zhi
; 41(10): 1855-1859, 2016 May.
Article
en Zh
| MEDLINE
| ID: mdl-28895332
ABSTRACT
In this study, the effect of D-cellobiose on oral bioavailability of gentiopicroside (GPS) was investigate. The influence of D-cellobiose on GPS was achieved by calculating the residual GPS after being degraded with ß-glucosidase or intestinal flora, and the data demonstrated D-cellobiose could inhibit the degradation of GPS in intestines; in bioavailability experiment, D-cellobiose could significantly improve the oral bioavailability (P<0.05) of GPS at the mass ratio of 1â¶5, 1â¶10 (GPS-D-cellobiose). D-cellobiose applied in this study may improve the oral bioavailability of GPS through delaying the degradation in intestines.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Celobiosa
/
Glucósidos Iridoides
Límite:
Humans
Idioma:
Zh
Año:
2016
Tipo del documento:
Article