Cardioprotective Effects of Exosomes and Their Potential Therapeutic Use.
Adv Exp Med Biol
; 998: 163-177, 2017.
Article
en En
| MEDLINE
| ID: mdl-28936739
ABSTRACT
Exosomes are membrane-contained vesicles released by various types of cells both in animals and human. They contain microRNAs and proteins and can travel to target cells, affecting their functions. There are specific factors on the surface of every exosomes, making sure that they will be taken up by certain type of cells. With these features, exosomes have been recognized to be one of the fundamental "messengers" for cell-cell communication. Recently, increased interest has been raised in exosomes since they were discovered to play an unneglectable role in preserving cardiac function and cardiomyocyte repair during stress. The widely explored stem cell therapy for cardiomyopathy uncovered the contribution of exosomes. Here we summarized cardioprotective effects of exosomes and their potential therapeutic use.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Regeneración
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Enfermedades Cardiovasculares
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Miocitos Cardíacos
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Trasplante de Células Madre
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Exosomas
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Miocardio
Límite:
Animals
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Humans
Idioma:
En
Año:
2017
Tipo del documento:
Article