Improved Calcium Scoring at Dual-Energy Computed Tomography Angiography Using a High-Z Contrast Element and Novel Material Separation Technique.
J Comput Assist Tomogr
; 42(3): 459-466, 2018.
Article
en En
| MEDLINE
| ID: mdl-28937491
ABSTRACT
OBJECTIVES:
The aim of this study was to compare the accuracy of existing dual-energy computed tomography (CT) angiography coronary artery calcium scoring methods to those obtained using an experimental tungsten-based contrast material and a recently described contrast material extraction process (CMEP).METHODS:
Phantom coronary arteries of varied diameters, with different densities and arcs of simulated calcified plaque, were sequentially filled with water, iodine, and tungsten contrast materials and scanned within a thorax phantom at rapid-kVp-switching dual-energy CT. Calcium and contrast density images were obtained by material decomposition (MD) and CMEP. Relative calcium scoring errors among the 4 reconstructed datasets were compared with a ground truth, 120-kVp dataset.RESULTS:
Compared with the 120-kVp dataset, tungsten CMEP showed a significantly lower mean absolute error in calcium score (6.2%, P < 0.001) than iodine CMEP, tungsten MD, and iodine MD (9.9%, 15.7%, and 40.8%, respectively).CONCLUSIONS:
Novel contrast elements and material separation techniques offer improved coronary artery calcium scoring accuracy and show potential to improve the use of dual-energy CT angiography in a clinical setting.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Calcinosis
/
Aumento de la Imagen
/
Imagen Radiográfica por Emisión de Doble Fotón
/
Fantasmas de Imagen
/
Medios de Contraste
/
Angiografía por Tomografía Computarizada
Idioma:
En
Año:
2018
Tipo del documento:
Article