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Infectious Bronchitis Virus Variants: Molecular Analysis and Pathogenicity Investigation.
Lin, Shu-Yi; Chen, Hui-Wen.
  • Lin SY; Department of Veterinary Medicine, National Taiwan University, Taipei 10617, Taiwan. susielin531@gmail.com.
  • Chen HW; Department of Veterinary Medicine, National Taiwan University, Taipei 10617, Taiwan. winnichen@ntu.edu.tw.
Int J Mol Sci ; 18(10)2017 Sep 22.
Article en En | MEDLINE | ID: mdl-28937583
ABSTRACT
Infectious bronchitis virus (IBV) variants constantly emerge and pose economic threats to poultry farms worldwide. Numerous studies on the molecular and pathogenic characterization of IBV variants have been performed between 2007 and 2017, which we have reviewed herein. We noted that viral genetic mutations and recombination events commonly gave rise to distinct IBV genotypes, serotypes and pathotypes. In addition to characterizing the S1 genes, full viral genomic sequencing, comprehensive antigenicity, and pathogenicity studies on emerging variants have advanced our understanding of IBV infections, which is valuable for developing countermeasures against IBV field outbreaks. This review of IBV variants provides practical value for understanding their phylogenetic relationships and epidemiology from both regional and worldwide viewpoints.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Genoma Viral / Virus de la Bronquitis Infecciosa Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Genoma Viral / Virus de la Bronquitis Infecciosa Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article