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DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs.
Janssen, Erin; Kumari, Sudha; Tohme, Mira; Ullas, Sumana; Barrera, Victor; Tas, Jeroen Mj; Castillo-Rama, Marcela; Bronson, Roderick T; Usmani, Shariq M; Irvine, Darrell J; Mempel, Thorsten R; Geha, Raif S.
  • Janssen E; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
  • Kumari S; Department of Bioengineering and Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Tohme M; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
  • Ullas S; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
  • Barrera V; Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
  • Tas JM; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
  • Castillo-Rama M; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
  • Bronson RT; Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
  • Usmani SM; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
  • Irvine DJ; Department of Bioengineering and Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
  • Mempel TR; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
  • Geha RS; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
JCI Insight ; 2(19)2017 10 05.
Article en En | MEDLINE | ID: mdl-28978806
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interleucina-2 / Linfocitos T Reguladores / Factores de Intercambio de Guanina Nucleótido / Sinapsis Inmunológicas / Tolerancia Inmunológica Límite: Animals Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Interleucina-2 / Linfocitos T Reguladores / Factores de Intercambio de Guanina Nucleótido / Sinapsis Inmunológicas / Tolerancia Inmunológica Límite: Animals Idioma: En Año: 2017 Tipo del documento: Article