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Safety and immunogenicity of rVSVΔG-ZEBOV-GP Ebola vaccine in adults and children in Lambaréné, Gabon: A phase I randomised trial.
Agnandji, Selidji T; Fernandes, José F; Bache, Emmanuel B; Obiang Mba, Régis M; Brosnahan, Jessica S; Kabwende, Lumeka; Pitzinger, Paul; Staarink, Pieter; Massinga-Loembe, Marguerite; Krähling, Verena; Biedenkopf, Nadine; Fehling, Sarah Katharina; Strecker, Thomas; Clark, David J; Staines, Henry M; Hooper, Jay W; Silvera, Peter; Moorthy, Vasee; Kieny, Marie-Paule; Adegnika, Akim A; Grobusch, Martin P; Becker, Stephan; Ramharter, Michael; Mordmüller, Benjamin; Lell, Bertrand; Krishna, Sanjeev; Kremsner, Peter G.
  • Agnandji ST; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Fernandes JF; Institut für Tropenmedizin, Universitätsklinikum Tübingen, Tübingen, Germany.
  • Bache EB; German Centre for Infection Research (DZIF) partner sites Universitätsklinikum Tübingen and Gießen-Marburg-Langen, Germany.
  • Obiang Mba RM; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Brosnahan JS; Institut für Tropenmedizin, Universitätsklinikum Tübingen, Tübingen, Germany.
  • Kabwende L; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Pitzinger P; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Staarink P; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Massinga-Loembe M; Institut für Tropenmedizin, Universitätsklinikum Tübingen, Tübingen, Germany.
  • Krähling V; German Centre for Infection Research (DZIF) partner sites Universitätsklinikum Tübingen and Gießen-Marburg-Langen, Germany.
  • Biedenkopf N; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Fehling SK; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Strecker T; Institut für Tropenmedizin, Universitätsklinikum Tübingen, Tübingen, Germany.
  • Clark DJ; Bernhard Nocht Hospital for Tropical Diseases, Bernhard Nocht Institute for Tropical Medicine and University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Staines HM; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Hooper JW; Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands.
  • Silvera P; Centre de Recherches Médicales de Lambaréné, Lambaréné, Gabon.
  • Moorthy V; German Centre for Infection Research (DZIF) partner sites Universitätsklinikum Tübingen and Gießen-Marburg-Langen, Germany.
  • Kieny MP; Institute for Virology, Philipps-Universität Marburg, Marburg, Germany.
  • Adegnika AA; Institute for Virology, Philipps-Universität Marburg, Marburg, Germany.
  • Grobusch MP; Institute for Virology, Philipps-Universität Marburg, Marburg, Germany.
  • Becker S; Institute for Virology, Philipps-Universität Marburg, Marburg, Germany.
  • Ramharter M; Centre for Diagnostics and Antimicrobial Resistance, Institute for Infection & Immunity, St. George's, University of London, London, United Kingdom.
  • Mordmüller B; Centre for Diagnostics and Antimicrobial Resistance, Institute for Infection & Immunity, St. George's, University of London, London, United Kingdom.
  • Lell B; US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, United States of America.
  • Krishna S; World Health Organization, Geneva, Switzerland.
  • Kremsner PG; World Health Organization, Geneva, Switzerland.
PLoS Med ; 14(10): e1002402, 2017 Oct.
Article en En | MEDLINE | ID: mdl-28985239

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fiebre Hemorrágica Ebola / Vacunas contra el Virus del Ébola / Ebolavirus / Inmunidad Adaptativa / Inmunogenicidad Vacunal Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Adolescent / Adult / Child / Female / Humans / Male / Middle aged País como asunto: Africa Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fiebre Hemorrágica Ebola / Vacunas contra el Virus del Ébola / Ebolavirus / Inmunidad Adaptativa / Inmunogenicidad Vacunal Tipo de estudio: Clinical_trials / Diagnostic_studies Límite: Adolescent / Adult / Child / Female / Humans / Male / Middle aged País como asunto: Africa Idioma: En Año: 2017 Tipo del documento: Article