Synthesis of ß-Ketosulfonamides Derived from Amino Acids and Their Conversion to ß-Keto-&#945;,&#945;-difluorosulfonamides via Electrophilic Fluorination.

Synthesis of ß-Ketosulfonamides Derived from Amino Acids and Their Conversion to ß-Keto-α,α-difluorosulfonamides via Electrophilic Fluorination.

Soley, Jacob; Chiu, Edmond; Chung, Ryan; Green, Jeremy; Hein, Jason E; Taylor, Scott D.

Soley J; Department of Chemistry, University of Waterloo , 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada.
Chiu E; Department of Chemistry, University of Waterloo , 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada.
Chung R; University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
Green J; Vertex Pharmaceuticals , 50 Northern Avenue, Boston, Massachusetts 02210, United States.
Hein JE; University of British Columbia , 2036 Main Mall, Vancouver, British Columbia V6T 1Z1, Canada.
Taylor SD; Department of Chemistry, University of Waterloo , 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada.

J Org Chem ; 82(20): 11157-11165, 2017 10 20.

Article en En | MEDLINE | ID: mdl-29019682

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Idioma: En Año: 2017 Tipo del documento: Article