Ecdysone catabolism in the white mouse.

Girault, J P; Lafont, R; Kerb, U

Girault, J P; Lafont, R; Kerb, U.

Girault JP; Université René Descartes, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS U.A. 400, Paris, France.

Drug Metab Dispos ; 16(5): 716-20, 1988.

Article en En | MEDLINE | ID: mdl-2906596

RESUMEN

Ecdysone metabolism was investigated in the white mouse Mus musculus. It was shown to involve dehydroxylation at C-14, followed by reduction of ring B into a 6 alpha-hydroxy derivative and epimerization at C-3.

Asunto(s)

Ecdisona/metabolismo; Animales; Biotransformación; Cromatografía Líquida de Alta Presión; Masculino; Ratones; Estructura Molecular; Oxidación-Reducción

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