Synthesis and Antitumor Activity of Novel Arylpiperazine Derivatives Containing the Saccharin Moiety.

Chen, Hong; Xu, Bing-Bing; Sun, Tao; Zhou, Zhan; Ya, Hui-Yuan; Yuan, Mu

Chen, Hong; Xu, Bing-Bing; Sun, Tao; Zhou, Zhan; Ya, Hui-Yuan; Yuan, Mu.

Chen H; College of Food and Drug, Luoyang Normal University, 6# Jiqing Road, Luoyang 471934, China. chenwexpo@sina.com.
Xu BB; Pharmaceutical Research Center, Guangzhou Medical University, 195# Dongfengxi Road, Guangzhou 511436, China. yjxubb@163.com.
Sun T; College of Food and Drug, Luoyang Normal University, 6# Jiqing Road, Luoyang 471934, China. suntao2226@163.com.
Zhou Z; College of Food and Drug, Luoyang Normal University, 6# Jiqing Road, Luoyang 471934, China. zhouzhan0406@163.com.
Ya HY; College of Food and Drug, Luoyang Normal University, 6# Jiqing Road, Luoyang 471934, China. chenwexpo@163.com.
Yuan M; Pharmaceutical Research Center, Guangzhou Medical University, 195# Dongfengxi Road, Guangzhou 511436, China. mryuanmu838@sina.com.

Molecules ; 22(11)2017 Oct 29.

Article en En | MEDLINE | ID: mdl-29109383

Asunto(s)

Antineoplásicos/farmacología; Ensayos de Selección de Medicamentos Antitumorales/métodos; Sacarina/química; Antineoplásicos/química; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Diseño de Fármacos; Humanos; Estructura Molecular; Relación Estructura-Actividad

Palabras clave

CCK-8; arylpiperazine derivatives; cytotoxic activity; structure-activity relationship; synthesis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sacarina / Ensayos de Selección de Medicamentos Antitumorales / Antineoplásicos Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article

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