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X-ray Characterization and Structure-Based Optimization of Striatal-Enriched Protein Tyrosine Phosphatase Inhibitors.
Witten, Michael R; Wissler, Lisa; Snow, Melanie; Geschwindner, Stefan; Read, Jon A; Brandon, Nicholas J; Nairn, Angus C; Lombroso, Paul J; Käck, Helena; Ellman, Jonathan A.
  • Witten MR; Department of Chemistry, Yale University , New Haven, Connecticut 06520, United States.
  • Wissler L; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca , Gothenburg, Sweden.
  • Snow M; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca , Macclesfield SK10 4TG, United Kingdom.
  • Geschwindner S; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca , Gothenburg, Sweden.
  • Read JA; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca , Cambridge CB4 0WG, United Kingdom.
  • Brandon NJ; Neuroscience, Innovative Medicines and Early Development Biotech Unit, AstraZeneca , Cambridge, Massachusetts 02139, United States.
  • Nairn AC; Department of Psychiatry, Yale University , New Haven, Connecticut 06520, United States.
  • Lombroso PJ; Department of Psychiatry, Yale University , New Haven, Connecticut 06520, United States.
  • Käck H; Child Study Center, Yale University , New Haven, Connecticut 06520, United States.
  • Ellman JA; Discovery Sciences, Innovative Medicines and Early Development Biotech Unit, AstraZeneca , Gothenburg, Sweden.
J Med Chem ; 60(22): 9299-9319, 2017 11 22.
Article en En | MEDLINE | ID: mdl-29116812
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Proteínas Tirosina Fosfatasas no Receptoras / Organofosfonatos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sulfonamidas / Proteínas Tirosina Fosfatasas no Receptoras / Organofosfonatos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2017 Tipo del documento: Article