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Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.
Sun, Kaiqi; D'Alessandro, Angelo; Ahmed, Mostafa H; Zhang, Yujin; Song, Anren; Ko, Tzu-Ping; Nemkov, Travis; Reisz, Julie A; Wu, Hongyu; Adebiyi, Morayo; Peng, Zhangzhe; Gong, Jing; Liu, Hong; Huang, Aji; Wen, Yuan Edward; Wen, Alexander Q; Berka, Vladimir; Bogdanov, Mikhail V; Abdulmalik, Osheiza; Han, Leng; Tsai, Ah-Lim; Idowu, Modupe; Juneja, Harinder S; Kellems, Rodney E; Dowhan, William; Hansen, Kirk C; Safo, Martin K; Xia, Yang.
  • Sun K; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • D'Alessandro A; Graduate School of Biomedical Science, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Ahmed MH; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, 80045, USA.
  • Zhang Y; Department of Medicinal Chemistry, and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, 23298, USA.
  • Song A; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Ko TP; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Nemkov T; Department of Medicinal Chemistry, and The Institute for Structural Biology, Drug Discovery and Development, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, 23298, USA.
  • Reisz JA; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, 80045, USA.
  • Wu H; Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, 80045, USA.
  • Adebiyi M; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Peng Z; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Gong J; Graduate School of Biomedical Science, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Liu H; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Huang A; Department of Nephrology, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
  • Wen YE; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Wen AQ; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Berka V; Graduate School of Biomedical Science, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Bogdanov MV; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Abdulmalik O; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Han L; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Tsai AL; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Idowu M; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Juneja HS; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Kellems RE; Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
  • Dowhan W; Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Hansen KC; Department of Internal Medicine-Hematology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Safo MK; Department of Internal Medicine-Hematology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
  • Xia Y; Department of Internal Medicine-Hematology, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Sci Rep ; 7(1): 15281, 2017 11 10.
Article en En | MEDLINE | ID: mdl-29127281
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Esfingosina / Hemoglobina A / Hemoglobina Falciforme / Lisofosfolípidos / Eritrocitos Anormales / Anemia de Células Falciformes Límite: Animals / Female / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Esfingosina / Hemoglobina A / Hemoglobina Falciforme / Lisofosfolípidos / Eritrocitos Anormales / Anemia de Células Falciformes Límite: Animals / Female / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article