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Human primary liver cancer-derived organoid cultures for disease modeling and drug screening.
Broutier, Laura; Mastrogiovanni, Gianmarco; Verstegen, Monique Ma; Francies, Hayley E; Gavarró, Lena Morrill; Bradshaw, Charles R; Allen, George E; Arnes-Benito, Robert; Sidorova, Olga; Gaspersz, Marcia P; Georgakopoulos, Nikitas; Koo, Bon-Kyoung; Dietmann, Sabine; Davies, Susan E; Praseedom, Raaj K; Lieshout, Ruby; IJzermans, Jan N M; Wigmore, Stephen J; Saeb-Parsy, Kourosh; Garnett, Mathew J; van der Laan, Luc Jw; Huch, Meritxell.
  • Broutier L; The Wellcome Trust/CRUK Gurdon Institute, University of Cambridge, Cambridge, UK.
  • Mastrogiovanni G; The Wellcome Trust/CRUK Gurdon Institute, University of Cambridge, Cambridge, UK.
  • Verstegen MM; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Francies HE; Department of Surgery, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.
  • Gavarró LM; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Bradshaw CR; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Allen GE; The Wellcome Trust/CRUK Gurdon Institute, University of Cambridge, Cambridge, UK.
  • Arnes-Benito R; The Wellcome Trust/CRUK Gurdon Institute, University of Cambridge, Cambridge, UK.
  • Sidorova O; The Wellcome Trust/CRUK Gurdon Institute, University of Cambridge, Cambridge, UK.
  • Gaspersz MP; The Wellcome Trust/CRUK Gurdon Institute, University of Cambridge, Cambridge, UK.
  • Georgakopoulos N; Department of Surgery, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.
  • Koo BK; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
  • Dietmann S; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Davies SE; Wellcome Trust-Medical Research Council Stem Cell Institute, University of Cambridge, Cambridge, UK.
  • Praseedom RK; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Lieshout R; Department of Hepato Pancreato Biliary Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • IJzermans JNM; Department of Surgery, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.
  • Wigmore SJ; Department of Surgery, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.
  • Saeb-Parsy K; Department of Clinical Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK.
  • Garnett MJ; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
  • van der Laan LJ; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
  • Huch M; Department of Surgery, Erasmus MC-University Medical Center, Rotterdam, the Netherlands.
Nat Med ; 23(12): 1424-1435, 2017 Dec.
Article en En | MEDLINE | ID: mdl-29131160
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de los Conductos Biliares / Ensayos de Selección de Medicamentos Antitumorales / Organoides / Colangiocarcinoma / Carcinoma Hepatocelular / Cultivo Primario de Células / Neoplasias Hepáticas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias de los Conductos Biliares / Ensayos de Selección de Medicamentos Antitumorales / Organoides / Colangiocarcinoma / Carcinoma Hepatocelular / Cultivo Primario de Células / Neoplasias Hepáticas Tipo de estudio: Diagnostic_studies / Prognostic_studies / Screening_studies Límite: Animals / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article