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Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor.
Gorelenkova Miller, Olga; Cole, Kyle S; Emerson, Corey C; Allimuthu, Dharmaraja; Golczak, Marcin; Stewart, Phoebe L; Weerapana, Eranthie; Adams, Drew J; Mieyal, John J.
  • Gorelenkova Miller O; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America.
  • Cole KS; Department of Chemistry, Boston College, Chestnut Hill, Massachusetts, United States of America.
  • Emerson CC; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America.
  • Allimuthu D; Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America.
  • Golczak M; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America.
  • Stewart PL; Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, United States of America.
  • Weerapana E; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, United States of America.
  • Adams DJ; Cleveland Center for Membrane and Structural Biology, Case Western Reserve University, Cleveland, Ohio, United States of America.
  • Mieyal JJ; Department of Chemistry, Boston College, Chestnut Hill, Massachusetts, United States of America.
PLoS One ; 12(11): e0187991, 2017.
Article en En | MEDLINE | ID: mdl-29155853

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácidos Ftálicos / Microglía / Glutarredoxinas / Acetanilidas / Antiinflamatorios Límite: Animals Idioma: En Año: 2017 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ácidos Ftálicos / Microglía / Glutarredoxinas / Acetanilidas / Antiinflamatorios Límite: Animals Idioma: En Año: 2017 Tipo del documento: Article