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Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies.
Prabhu, Varun V; Talekar, Mala K; Lulla, Amriti R; Kline, C Leah B; Zhou, Lanlan; Hall, Junior; Van den Heuvel, A Pieter J; Dicker, David T; Babar, Jawad; Grupp, Stephan A; Garnett, Mathew J; McDermott, Ultan; Benes, Cyril H; Pu, Jeffrey J; Claxton, David F; Khan, Nadia; Oster, Wolfgang; Allen, Joshua E; El-Deiry, Wafik S.
  • Prabhu VV; a Oncoceutics, Inc. , Philadelphia , PA.
  • Talekar MK; b The Children's Hospital of Philadelphia , Philadelphia , PA.
  • Lulla AR; c Fox Chase Cancer Center , Philadelphia , PA.
  • Kline CLB; c Fox Chase Cancer Center , Philadelphia , PA.
  • Zhou L; c Fox Chase Cancer Center , Philadelphia , PA.
  • Hall J; b The Children's Hospital of Philadelphia , Philadelphia , PA.
  • Van den Heuvel APJ; d Penn State College of Medicine , Hershey , PA.
  • Dicker DT; c Fox Chase Cancer Center , Philadelphia , PA.
  • Babar J; c Fox Chase Cancer Center , Philadelphia , PA.
  • Grupp SA; b The Children's Hospital of Philadelphia , Philadelphia , PA.
  • Garnett MJ; e Wellcome Trust Sanger Institute , Hinxton , UK.
  • McDermott U; e Wellcome Trust Sanger Institute , Hinxton , UK.
  • Benes CH; f Massachusetts General Hospital, Harvard Medical School , Boston , MA.
  • Pu JJ; d Penn State College of Medicine , Hershey , PA.
  • Claxton DF; d Penn State College of Medicine , Hershey , PA.
  • Khan N; c Fox Chase Cancer Center , Philadelphia , PA.
  • Oster W; a Oncoceutics, Inc. , Philadelphia , PA.
  • Allen JE; a Oncoceutics, Inc. , Philadelphia , PA.
  • El-Deiry WS; a Oncoceutics, Inc. , Philadelphia , PA.
Cell Cycle ; 17(4): 468-478, 2018.
Article en En | MEDLINE | ID: mdl-29157092

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Apoptosis / Compuestos Heterocíclicos de 4 o más Anillos / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Apoptosis / Compuestos Heterocíclicos de 4 o más Anillos / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article