Limonoids from the roots of Trichilia sinensis and their cytotoxicities.
Arch Pharm Res
; 41(12): 1170-1177, 2018 Dec.
Article
en En
| MEDLINE
| ID: mdl-29170993
ABSTRACT
Six new compounds (1-4, 8, 10), along with six known limonoids (5-7, 9, 11, 12), were isolated from the roots of Trichilia sinensis. Their structures were elucidated on the basis of extensive spectroscopic methods including 1H NMR, 13C NMR, DEPT, HSQC, HMBC, 1H-1H COSY and ROESY experiments, as well as by comparison with the literature. All the compounds were evaluated for cytotoxicities against K562, SGC-7901 and BEL-7402 cell lines. Compounds 2, 7, 10, 11, and 12 showed weak inhibitory activity to the selected cell lines.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Raíces de Plantas
/
Meliaceae
/
Limoninas
/
Antineoplásicos Fitogénicos
Límite:
Humans
Idioma:
En
Año:
2018
Tipo del documento:
Article