AP-4 mediates export of ATG9A from the <i>trans</i>-Golgi network to promote autophagosome formation.

Mattera, Rafael; Park, Sang Yoon; De Pace, Raffaella; Guardia, Carlos M; Bonifacino, Juan S

AP-4 mediates export of ATG9A from the trans-Golgi network to promote autophagosome formation.

Mattera, Rafael; Park, Sang Yoon; De Pace, Raffaella; Guardia, Carlos M; Bonifacino, Juan S.

Mattera R; Cell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
Park SY; Cell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
De Pace R; Cell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
Guardia CM; Cell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892.
Bonifacino JS; Cell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 juan.bonifacino@nih.gov.

Proc Natl Acad Sci U S A ; 114(50): E10697-E10706, 2017 12 12.

Article en En | MEDLINE | ID: mdl-29180427

Asunto(s)

Complejo 4 de Proteína Adaptadora/metabolismo; Autofagosomas/metabolismo; Proteínas Relacionadas con la Autofagia/metabolismo; Aparato de Golgi/metabolismo; Proteínas de la Membrana/metabolismo; Proteínas de Transporte Vesicular/metabolismo; Complejo 4 de Proteína Adaptadora/genética; Proteínas Adaptadoras del Transporte Vesicular/metabolismo; Secuencias de Aminoácidos; Animales; Autofagia; Línea Celular Tumoral; Técnicas de Silenciamiento del Gen; Células HeLa; Humanos; Ratones; Ratones Endogámicos C57BL; Proteínas Asociadas a Microtúbulos/metabolismo; Modelos Moleculares; Paraplejía Espástica Hereditaria/genética; Paraplejía Espástica Hereditaria/metabolismo

Palabras clave

AP-4; ATG9A; adaptor protein complexes; autophagy; protein sorting

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas de Transporte Vesicular / Complejo 4 de Proteína Adaptadora / Autofagosomas / Proteínas Relacionadas con la Autofagia / Aparato de Golgi / Proteínas de la Membrana Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2017 Tipo del documento: Article

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