Efficacy of ultrasound-guided core needle biopsy in cervical lymphadenopathy: A retrospective study of 6,695 cases.
Eur Radiol
; 28(5): 1809-1817, 2018 May.
Article
en En
| MEDLINE
| ID: mdl-29188372
ABSTRACT
OBJECTIVES:
To determine the diagnostic yield of ultrasound-guided core needle biopsy (US-CNB) in cervical lymphadenopathy and identify the factors influencing the diagnostic accuracy of US-CNB.METHODS:
We retrospectively reviewed the records of 6,603 patients with cervical lymphadenopathy who underwent 6695 US-CNB procedures between 2004 and 2017.RESULTS:
Adequate specimens were obtained in 92.19 % (6,172/6,695) of cases. Most lymph nodes (67.65 %) were malignant (metastatic carcinoma 4,131; lymphoma 398). The overall accuracy of US-CNB for differentiating benign from malignant lesions was 91.70 % (6,139/6,695). Among biopsies in which adequate material was obtained, the sensitivity, specificity and accuracy of US-CNB were 99.70 %, 100 % and 99.46 %, respectively. The success or failure of US-CNB for the diagnosis of lymphadenopathy was significantly correlated with node size, nature (malignant vs. benign), and location as well as penetration depth, but not with needle size (p = 0.665), number of core tissues obtained (p = 0.324), or history of malignancy (p = 0.060). There were no major procedure-related complications.CONCLUSIONS:
US-CNB is a safe and effective method of diagnosing cervical lymphadenopathy, and our findings may help optimise the sampling procedure by maximising its diagnostic accuracy and preserving its minimally invasive nature. KEY POINTS ⢠US-CNB is useful for the diagnosis of cervical lymphadenopathy. ⢠US-CNB is safe to perform on lymph nodes located near vital structures. ⢠Larger, malignant, level IV lymph nodes yield sufficient tissue samples more easily.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Ultrasonografía
/
Biopsia con Aguja Gruesa
/
Biopsia Guiada por Imagen
/
Linfadenopatía
/
Neoplasias de Cabeza y Cuello
/
Ganglios Linfáticos
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Límite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Año:
2018
Tipo del documento:
Article