Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.

Wutz, Gordana; Várnai, Csilla; Nagasaka, Kota; Cisneros, David A; Stocsits, Roman R; Tang, Wen; Schoenfelder, Stefan; Jessberger, Gregor; Muhar, Matthias; Hossain, M Julius; Walther, Nike; Koch, Birgit; Kueblbeck, Moritz; Ellenberg, Jan; Zuber, Johannes; Fraser, Peter; Peters, Jan-Michael

Wutz, Gordana; Várnai, Csilla; Nagasaka, Kota; Cisneros, David A; Stocsits, Roman R; Tang, Wen; Schoenfelder, Stefan; Jessberger, Gregor; Muhar, Matthias; Hossain, M Julius; Walther, Nike; Koch, Birgit; Kueblbeck, Moritz; Ellenberg, Jan; Zuber, Johannes; Fraser, Peter; Peters, Jan-Michael.

Wutz G; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
Várnai C; Nuclear Dynamics Programme, The Babraham Institute, Babraham Research Campus, Cambridge, UK.
Nagasaka K; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
Cisneros DA; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
Stocsits RR; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
Tang W; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
Schoenfelder S; Nuclear Dynamics Programme, The Babraham Institute, Babraham Research Campus, Cambridge, UK.
Jessberger G; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
Muhar M; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
Hossain MJ; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Walther N; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Koch B; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Kueblbeck M; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Ellenberg J; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Zuber J; Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.
Fraser P; Nuclear Dynamics Programme, The Babraham Institute, Babraham Research Campus, Cambridge, UK.
Peters JM; Department of Biological Science, Florida State University, Tallahassee, FL, USA.

EMBO J ; 36(24): 3573-3599, 2017 12 15.

Article en En | MEDLINE | ID: mdl-29217591

Asunto(s)

Factor de Unión a CCCTC/metabolismo; Proteínas Portadoras/metabolismo; Proteínas de Ciclo Celular/metabolismo; Cromatina/genética; Proteínas Cromosómicas no Histona/metabolismo; Proteínas de Unión al ADN/metabolismo; Proteínas Nucleares/metabolismo; Proteínas Proto-Oncogénicas/metabolismo; Factores de Transcripción/metabolismo; Factor de Unión a CCCTC/genética; Proteínas Portadoras/genética; Proteínas de Ciclo Celular/genética; Proteínas Cromosómicas no Histona/genética; Cromosomas/genética; Proteínas de Unión al ADN/genética; Genoma Humano/genética; Células HeLa; Humanos; Proteínas Nucleares/genética; Proteínas Proto-Oncogénicas/genética; Factores de Transcripción/genética; Cohesinas

Palabras clave

chromatin condensation; chromatin structure; genome organization; loop extrusion; vermicelli

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Proteínas Nucleares / Cromatina / Proteínas Cromosómicas no Histona / Proteínas Portadoras / Proteínas Proto-Oncogénicas / Proteínas de Ciclo Celular / Proteínas de Unión al ADN / Factor de Unión a CCCTC Tipo de estudio: Risk_factors_studies Límite: Humans Idioma: En Año: 2017 Tipo del documento: Article

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