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Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment.
Steggerda, Susanne M; Bennett, Mark K; Chen, Jason; Emberley, Ethan; Huang, Tony; Janes, Julie R; Li, Weiqun; MacKinnon, Andrew L; Makkouk, Amani; Marguier, Gisele; Murray, Peter J; Neou, Silinda; Pan, Alison; Parlati, Francesco; Rodriguez, Mirna L M; Van de Velde, Lee-Ann; Wang, Tracy; Works, Melissa; Zhang, Jing; Zhang, Winter; Gross, Matthew I.
  • Steggerda SM; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA. ssteggerda@calithera.com.
  • Bennett MK; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Chen J; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Emberley E; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Huang T; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Janes JR; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Li W; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • MacKinnon AL; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Makkouk A; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Marguier G; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Murray PJ; Max Planck Institute for Biochemistry, Martinsried, Germany.
  • Neou S; Departments of Infectious Diseases and Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Pan A; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Parlati F; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Rodriguez MLM; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Van de Velde LA; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Wang T; Departments of Infectious Diseases and Immunology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Works M; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Zhang J; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Zhang W; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
  • Gross MI; Calithera Biosciences, 343 Oyster Point Boulevard, Suite 200, South San Francisco, CA, 94080, USA.
J Immunother Cancer ; 5(1): 101, 2017 12 19.
Article en En | MEDLINE | ID: mdl-29254508
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arginasa / Pirrolidinas / Células Mieloides / Bibliotecas de Moléculas Pequeñas / Microambiente Tumoral / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Arginasa / Pirrolidinas / Células Mieloides / Bibliotecas de Moléculas Pequeñas / Microambiente Tumoral / Neoplasias Límite: Animals / Female / Humans / Male Idioma: En Año: 2017 Tipo del documento: Article