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Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.
Gao, Xue; Tao, Yong; Lamas, Veronica; Huang, Mingqian; Yeh, Wei-Hsi; Pan, Bifeng; Hu, Yu-Juan; Hu, Johnny H; Thompson, David B; Shu, Yilai; Li, Yamin; Wang, Hongyang; Yang, Shiming; Xu, Qiaobing; Polley, Daniel B; Liberman, M Charles; Kong, Wei-Jia; Holt, Jeffrey R; Chen, Zheng-Yi; Liu, David R.
  • Gao X; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Tao Y; Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Lamas V; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02141, USA.
  • Huang M; Department of Otolaryngology and Program in Neuroscience, Harvard Medical School and Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.
  • Yeh WH; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
  • Pan B; Department of Otolaryngology and Program in Neuroscience, Harvard Medical School and Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.
  • Hu YJ; Department of Otolaryngology and Program in Neuroscience, Harvard Medical School and Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.
  • Hu JH; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Thompson DB; Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Shu Y; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02141, USA.
  • Li Y; Program in Speech and Hearing Bioscience and Technology, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Wang H; Departments of Otolaryngology and Neurology, F.M. Kirby Neurobiology Center Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
  • Yang S; Department of Otolaryngology and Program in Neuroscience, Harvard Medical School and Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.
  • Xu Q; Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China.
  • Polley DB; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Liberman MC; Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Kong WJ; Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02141, USA.
  • Holt JR; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Chen ZY; Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts 02138, USA.
  • Liu DR; Department of Otolaryngology and Program in Neuroscience, Harvard Medical School and Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA.
Nature ; 553(7687): 217-221, 2018 01 11.
Article en En | MEDLINE | ID: mdl-29258297
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Terapia Genética / Proteínas Asociadas a CRISPR / Edición Génica / Genes Dominantes / Pérdida Auditiva Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Terapia Genética / Proteínas Asociadas a CRISPR / Edición Génica / Genes Dominantes / Pérdida Auditiva Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article