A Single Amino Acid Change in the Marburg Virus Glycoprotein Arises during Serial Cell Culture Passages and Attenuates the Virus in a Macaque Model of Disease.

Alfson, Kendra J; Avena, Laura E; Delgado, Jenny; Beadles, Michael W; Patterson, Jean L; Carrion, Ricardo; Griffiths, Anthony

Alfson, Kendra J; Avena, Laura E; Delgado, Jenny; Beadles, Michael W; Patterson, Jean L; Carrion, Ricardo; Griffiths, Anthony.

Alfson KJ; Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Avena LE; University of Texas Health Science Center, San Antonio, Texas, USA.
Delgado J; Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Beadles MW; Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Patterson JL; Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Carrion R; Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, USA.
Griffiths A; Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, USA.

mSphere ; 3(1)2018.

Article en En | MEDLINE | ID: mdl-29299527