Yield of family screening in patients with isolated bicuspid aortic valve in a general hospital.
Int J Cardiol
; 255: 55-58, 2018 Mar 15.
Article
en En
| MEDLINE
| ID: mdl-29329770
ABSTRACT
AIM:
To determine the prevalence of unidentified bicuspid aortic valve (BAV) or aortic dilatation (>40mm) in first degree relatives (FDR) of patients with isolated BAV in a general hospital. METHODS ANDRESULTS:
Patients with isolated BAV received information advising cardiac screening of their FDR. Referred and screened were 134 FDR of 54 adult index patients with isolated BAV (median 2 per index patient). FDR's mean age was 49years (range 16-83years) and 41% were male. They comprised 5 parents (3.7%), 52 siblings (39%) and 77 offspring (57%). Among these FDR, the prevalence of BAV was 6.0% (8 patients). In FDR without BAV, 10 (7.5%) had aortic dilatation. 'Familial BAV' was present in 9/54 families (17%).CONCLUSION:
In a general hospital, screening of FDR of patients with isolated BAV resulted in a substantial yield of 13% new cases with BAV or aortic dilatation without BAV.Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Válvula Aórtica
/
Familia
/
Tamizaje Masivo
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Enfermedades de las Válvulas Cardíacas
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Hospitales Generales
Tipo de estudio:
Diagnostic_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Adolescent
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Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Año:
2018
Tipo del documento:
Article