On the folding of a structurally complex protein to its metastable active state.

Giri Rao, V V Hemanth; Gosavi, Shachi

Giri Rao, V V Hemanth; Gosavi, Shachi.

Giri Rao VVH; Simons Centre for the Study of Living Machines, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore-560065, India.
Gosavi S; Simons Centre for the Study of Living Machines, National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore-560065, India shachi@ncbs.res.in.

Proc Natl Acad Sci U S A ; 115(9): 1998-2003, 2018 02 27.

Article en En | MEDLINE | ID: mdl-29343647

Asunto(s)

Pliegue de Proteína; alfa 1-Antitripsina/química; Dominio Catalítico; Simulación por Computador; Modelos Químicos; Modelos Moleculares; Conformación Proteica

Palabras clave

alternate folded conformations; kinetic trap; protein folding simulations; reactive center loop; α1-antitrypsin

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Alfa 1-Antitripsina / Pliegue de Proteína Tipo de estudio: Prognostic_studies Idioma: En Año: 2018 Tipo del documento: Article

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