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HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression.
Warburton, Alix; Redmond, Catherine J; Dooley, Katharine E; Fu, Haiqing; Gillison, Maura L; Akagi, Keiko; Symer, David E; Aladjem, Mirit I; McBride, Alison A.
  • Warburton A; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Redmond CJ; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Dooley KE; Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Fu H; Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.
  • Gillison ML; Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America.
  • Akagi K; Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America.
  • Symer DE; Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America.
  • Aladjem MI; Human Cancer Genetics Program, Department of Cancer Biology and Genetics, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America.
  • McBride AA; Department of Biomedical Informatics (adjunct), The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States of America.
PLoS Genet ; 14(1): e1007179, 2018 01.
Article en En | MEDLINE | ID: mdl-29364907
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Regulación Viral de la Expresión Génica / Integración Viral / Papillomavirus Humano 16 / Genes Virales Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Regulación Viral de la Expresión Génica / Integración Viral / Papillomavirus Humano 16 / Genes Virales Límite: Humans Idioma: En Año: 2018 Tipo del documento: Article