Peri-procedural antibiotic prophylaxis in ventricular septal defect: a case study to re-visit guidelines.

Garg, Nadish; Nayyar, Mannu; Khouzam, Rami N; Salem, Salem A; Ardeshna, Devarshi.

Garg N; Department of Cardiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Nayyar M; Department of Cardiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Khouzam RN; Department of Cardiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Salem SA; Department of Cardiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Ardeshna D; Medical Student, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Ann Transl Med ; 6(1): 18, 2018 Jan.

Article en En | MEDLINE | ID: mdl-29404364

ABSTRACT

The current American Heart Association (AHA)/American College of Cardiology (ACC) guidelines do not recommend antibiotic prophylaxis for infective endocarditis (IE) in patients with acyanotic congenital valvular heart disease due to lack of any proven benefit and potential harm associated with antibiotics. As recognized by the guidelines, some acyanotic congenital heart disease, such as ventricular septal defects (VSDs), are associated with a high velocity jet and pose a greater risk of peri-procedural endocarditis. We suggest that an acyanotic congenital heart disease with high velocity jet should be considered for antibiotic prophylaxis for IE.

Palabras clave

Ventricular septal defect (VSD); antibiotic prophylaxis; infective endocarditis (IE)