Digit ratio (2D:4D) in Chinese women with gastric cancer.
Am J Hum Biol
; 30(3): e23109, 2018 05.
Article
en En
| MEDLINE
| ID: mdl-29417657
ABSTRACT
OBJECTIVES:
Digit ratio, especially the second-to-fourth digit ratio (2D4D), is a proxy indicator for prenatal exposure and sensitivity to sexual hormones which may influence the susceptibility to certain cancers. The aim of the present study was to investigate whether there is a possible association between 2D4D and gastric cancer (GCA) in north Chinese women.METHODS:
Photographs of the left and right hands of 167 women (controls 113; patients 54) were collected. Left hand, right hand, and right minus left hand (Dr-l) 2D4D were analyzed and compared.RESULTS:
The GCA group presented significantly lower 2D4D than controls (left P < .01; right P < .05). No significant difference was observed in Dr-l between the two groups. In patients, there were no correlations between 2D4D and age at GCA or tumor staging.CONCLUSIONS:
Decreased 2D4D (especially of the left hand) may suggest a higher prenatal testosterone (lower prenatal estrogen) exposure in north Chinese women with GCA.
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Gástricas
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Dedos
Tipo de estudio:
Observational_studies
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Risk_factors_studies
Límite:
Adult
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Aged
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Female
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Humans
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Middle aged
Idioma:
En
Año:
2018
Tipo del documento:
Article