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Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancers.
Kawakami, Masanori; Mustachio, Lisa Maria; Zheng, Lin; Chen, Yulong; Rodriguez-Canales, Jaime; Mino, Barbara; Kurie, Jonathan M; Roszik, Jason; Villalobos, Pamela Andrea; Thu, Kelsie L; Silvester, Jennifer; Cescon, David W; Wistuba, Ignacio I; Mak, Tak W; Liu, Xi; Dmitrovsky, Ethan.
  • Kawakami M; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Mustachio LM; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Zheng L; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Chen Y; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Rodriguez-Canales J; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Mino B; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Kurie JM; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Roszik J; Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Villalobos PA; Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Thu KL; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Silvester J; The Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada.
  • Cescon DW; The Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada.
  • Wistuba II; The Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada.
  • Mak TW; Department of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada.
  • Liu X; Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
  • Dmitrovsky E; The Campbell Family Institute for Breast Cancer Research, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada; Tak.Mak@uhnresearch.ca.
Proc Natl Acad Sci U S A ; 115(8): 1913-1918, 2018 02 20.
Article en En | MEDLINE | ID: mdl-29434041
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Poliploidía / Proteínas Serina-Treonina Quinasas / Apoptosis / Indazoles / Indoles Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Poliploidía / Proteínas Serina-Treonina Quinasas / Apoptosis / Indazoles / Indoles Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article