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The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis.
Schneeweiss, Mathias; Peter, Barbara; Bibi, Siham; Eisenwort, Gregor; Smiljkovic, Dubravka; Blatt, Katharina; Jawhar, Mohamad; Berger, Daniela; Stefanzl, Gabriele; Herndlhofer, Susanne; Greiner, Georg; Hoermann, Gregor; Hadzijusufovic, Emir; Gleixner, Karoline V; Bettelheim, Peter; Geissler, Klaus; Sperr, Wolfgang R; Reiter, Andreas; Arock, Michel; Valent, Peter.
  • Schneeweiss M; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
  • Peter B; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.
  • Bibi S; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
  • Eisenwort G; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.
  • Smiljkovic D; Laboratoire de Biologie et Pharmacologie Appliquee, CNRS UMR 8113, Ecole Normale Superieure de Cachan, France.
  • Blatt K; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
  • Jawhar M; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.
  • Berger D; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
  • Stefanzl G; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
  • Herndlhofer S; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.
  • Greiner G; Department of Hematology and Oncology, University Medical Centre Mannheim and Medical Faculty Mannheim, Heidelberg University, Germany.
  • Hoermann G; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.
  • Hadzijusufovic E; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.
  • Gleixner KV; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
  • Bettelheim P; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.
  • Geissler K; Department of Laboratory Medicine, Medical University of Vienna, Austria.
  • Sperr WR; Department of Laboratory Medicine, Medical University of Vienna, Austria.
  • Reiter A; Ludwig Boltzmann Cluster Oncology, Medical University of Vienna, Austria.
  • Arock M; Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Austria.
  • Valent P; Department for Companion Animals and Horses, University Clinic for Small Animals, Internal Medicine Small Animals, University of Veterinary Medicine Vienna, Austria.
Haematologica ; 103(5): 799-809, 2018 05.
Article en En | MEDLINE | ID: mdl-29439183
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mielógena Crónica BCR-ABL Positiva / Proteínas Proto-Oncogénicas c-kit / Receptor alfa de Factor de Crecimiento Derivado de Plaquetas / Mastocitosis Sistémica / Inhibidores de Proteínas Quinasas / Proliferación Celular / Mastocitos Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Leucemia Mielógena Crónica BCR-ABL Positiva / Proteínas Proto-Oncogénicas c-kit / Receptor alfa de Factor de Crecimiento Derivado de Plaquetas / Mastocitosis Sistémica / Inhibidores de Proteínas Quinasas / Proliferación Celular / Mastocitos Límite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2018 Tipo del documento: Article