Oral lesions as an important marker for HIV progression.
Dermatol Online J
; 23(9)2017 Sep 15.
Article
en En
| MEDLINE
| ID: mdl-29469724
ABSTRACT
BACKGROUND:
Oral hairy leukoplakia (OHL) is a benign lesion caused by Epstein-Barr virus (EBV) replication in the oral epithelium affecting the borders of the tongue. It is strongly associated with immunosuppression, especially in HIV+ adults but is uncommon in pediatric population. The aim of the study is to show the importance of the correct diagnosis of OHL and its influence on HIV treatment.We report two cases of HIV+ adolescent patients that presented with leukoplakic lesions on the border of the tongue, suggestive of OHL. OHL diagnosis was confirmed in only one case through EBV in situ hybridization. After confirmation of the diagnosis, the patient with OHL was referred to an infectious disease specialist with the decision to start antiretroviral therapy.CONCLUSION:
OHL definitive diagnosis can help clinical management of pediatric HIV+ patients.
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Banco de datos:
MEDLINE
Asunto principal:
ADN Viral
/
Infecciones por VIH
/
Leucoplasia Vellosa
/
Herpesvirus Humano 4
/
Queratosis
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Prognostic_studies
Límite:
Adolescent
/
Female
/
Humans
Idioma:
En
Año:
2017
Tipo del documento:
Article