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Bicyclo((aryl)methyl)benzamides as inhibitors of GlyT1.
Varnes, Jeffrey G; Xiong, Hui; Forst, Janet M; Holmquist, Christopher R; Ernst, Glen E; Frietze, William; Dembofsky, Bruce; Andisik, Don W; Palmer, William E; Hinkley, Lindsay; Steelman, Gary B; Wilkins, Deidre E; Tian, Gaochao; Jonak, Gerald; Potts, William M; Wang, Xia; Brugel, Todd A; Alhambra, Cristóbal; Wood, Michael W; Veale, Chris A; Albert, Jeffrey S.
  • Varnes JG; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA. Electronic address: jeffrey.varnes@astrazeneca.com.
  • Xiong H; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Forst JM; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Holmquist CR; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Ernst GE; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Frietze W; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Dembofsky B; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Andisik DW; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Palmer WE; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Hinkley L; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Steelman GB; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Wilkins DE; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Tian G; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Jonak G; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Potts WM; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Wang X; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Brugel TA; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Alhambra C; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Wood MW; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Veale CA; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.
  • Albert JS; Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA. Electronic address: jeffrey.albert@intellisynrd.com.
Bioorg Med Chem Lett ; 28(6): 1043-1049, 2018 04 01.
Article en En | MEDLINE | ID: mdl-29486970
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Benzamidas / Compuestos Bicíclicos con Puentes / Proteínas de Transporte de Glicina en la Membrana Plasmática Límite: Animals / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Benzamidas / Compuestos Bicíclicos con Puentes / Proteínas de Transporte de Glicina en la Membrana Plasmática Límite: Animals / Humans / Male Idioma: En Año: 2018 Tipo del documento: Article