Mass spectrometric evidence for neuropeptide-amidating enzymes in <b><i>Caenorhabditis elegans</i></b>.

Van Bael, Sven; Watteyne, Jan; Boonen, Kurt; De Haes, Wouter; Menschaert, Gerben; Ringstad, Niels; Horvitz, H Robert; Schoofs, Liliane; Husson, Steven J; Temmerman, Liesbet

Mass spectrometric evidence for neuropeptide-amidating enzymes in Caenorhabditis elegans.

Van Bael, Sven; Watteyne, Jan; Boonen, Kurt; De Haes, Wouter; Menschaert, Gerben; Ringstad, Niels; Horvitz, H Robert; Schoofs, Liliane; Husson, Steven J; Temmerman, Liesbet.

Van Bael S; From the Department of Biology, KU Leuven (University of Leuven), Naamsestraat 59, B-3000 Leuven, Belgium, sven.vanbael@kuleuven.be.
Watteyne J; From the Department of Biology, KU Leuven (University of Leuven), Naamsestraat 59, B-3000 Leuven, Belgium.
Boonen K; From the Department of Biology, KU Leuven (University of Leuven), Naamsestraat 59, B-3000 Leuven, Belgium.
De Haes W; From the Department of Biology, KU Leuven (University of Leuven), Naamsestraat 59, B-3000 Leuven, Belgium.
Menschaert G; the Laboratory of Bioinformatics and Computational Genomics (BioBix), Department of Mathematical Modelling, Ghent University, B-9000 Ghent, Belgium.
Ringstad N; The Helen L. and Martin S. Kimmel Center for Biology and Medicine at the Skirball Institute of Biomolecular Medicine, Department of Cell Biology, NYU Langone Medical Center, New York, New York 10016.
Horvitz HR; the Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, and.
Schoofs L; From the Department of Biology, KU Leuven (University of Leuven), Naamsestraat 59, B-3000 Leuven, Belgium.
Husson SJ; SPHERE-Systemic Physiological and Ecotoxicological Research, Department of Biology, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp, Belgium.
Temmerman L; From the Department of Biology, KU Leuven (University of Leuven), Naamsestraat 59, B-3000 Leuven, Belgium, liesbet.temmerman@kuleuven.be.

J Biol Chem ; 293(16): 6052-6063, 2018 04 20.

Article en En | MEDLINE | ID: mdl-29487130

Asunto(s)

Amidina-Liasas/metabolismo; Proteínas de Caenorhabditis elegans/metabolismo; Caenorhabditis elegans/metabolismo; Oxigenasas de Función Mixta/metabolismo; Complejos Multienzimáticos/metabolismo; Neuropéptidos/metabolismo; Amidina-Liasas/química; Amidina-Liasas/genética; Secuencia de Aminoácidos; Animales; Vías Biosintéticas; Caenorhabditis elegans/química; Caenorhabditis elegans/genética; Proteínas de Caenorhabditis elegans/química; Proteínas de Caenorhabditis elegans/genética; Cobre/metabolismo; Eliminación de Gen; Humanos; Oxigenasas de Función Mixta/química; Oxigenasas de Función Mixta/genética; Complejos Multienzimáticos/química; Complejos Multienzimáticos/genética; Mutación; Neuropéptidos/genética; Alineación de Secuencia; Espectrometría de Masas en Tándem

Palabras clave

Caenorhabditis elegans (C. elegans); PAL; PAM; PHM; amidation; copper monooxygenase; mass spectrometry (MS); neuropeptide; peptides; peptidomics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neuropéptidos / Caenorhabditis elegans / Amidina-Liasas / Proteínas de Caenorhabditis elegans / Oxigenasas de Función Mixta / Complejos Multienzimáticos Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article

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