[Can Pravastatin influence Pregnancies at High-risk for Preeclampsia?] / Pravastatin ­ Ein Lipidsenker zur Präeklampsie-Prophylaxe und Therapieoption?

ABSTRACT

Statins seem to positively influence the inflammatory, anti-angiogenic milieu of pregnancies with underlying placental ischemia by their pleiotropic effects. This might prevent, ameliorate and delay preeclampsia. To confirm the benefits of pravastatin on gestational age at birth as well as clinic and angiogenic markers in pregnancies at high-risk for preeclampsia, the Department of Obstetrics at the University Hospital Leipzig plans a randomized, double-blinded, placebo-controlled feasibility study.