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A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism.
Douam, Florian; Fusil, Floriane; Enguehard, Margot; Dib, Linda; Nadalin, Francesca; Schwaller, Loïc; Hrebikova, Gabriela; Mancip, Jimmy; Mailly, Laurent; Montserret, Roland; Ding, Qiang; Maisse, Carine; Carlot, Emilie; Xu, Ke; Verhoeyen, Els; Baumert, Thomas F; Ploss, Alexander; Carbone, Alessandra; Cosset, François-Loïc; Lavillette, Dimitri.
  • Douam F; CIRI-International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France.
  • Fusil F; CNRS UMR5557 Microbial ecology, Université Claude Bernard Lyon 1, INRA, UMR1418, Villeurbanne, France.
  • Enguehard M; Department of Molecular Biology, Princeton University, Princeton NJ, United States of America.
  • Dib L; CIRI-International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France.
  • Nadalin F; CNRS UMR5557 Microbial ecology, Université Claude Bernard Lyon 1, INRA, UMR1418, Villeurbanne, France.
  • Schwaller L; University of Lyon, Université Claude Bernard Lyon1, INRA, EPHE, IVPC, Viral Infections and Comparative Pathology, UMR754, Lyon, France.
  • Hrebikova G; Institut Hospitalo-Universitaire, Pôle Hépato-digestif, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
  • Mancip J; Molecular Phylogenetics and Speciation, Département d'écologie et évolution, Université de Lausanne, Lausanne, Suisse.
  • Mailly L; Sorbonne Université, CNRS, IBPS, UMR 7238, Laboratoire de Biologie Computationnelle et Quantitative, Paris, France.
  • Montserret R; Mathematical Institute, Leiden University, Leiden, The Netherlands.
  • Ding Q; Department of Molecular Biology, Princeton University, Princeton NJ, United States of America.
  • Maisse C; CIRI-International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France.
  • Carlot E; Inserm, U1110, Institut de Recherche sur les Maladies Virales et Hépatiques, Strasbourg, France.
  • Xu K; Université de Strasbourg, Strasbourg, France.
  • Verhoeyen E; Institut de Biologie et Chimie des Protéines, Bases Moléculaires et Structurales des Systèmes Infectieux, Labex Ecofect, UMR 5086 CNRS, Université de Lyon, Lyon, France.
  • Baumert TF; Department of Molecular Biology, Princeton University, Princeton NJ, United States of America.
  • Ploss A; University of Lyon, Université Claude Bernard Lyon1, INRA, EPHE, IVPC, Viral Infections and Comparative Pathology, UMR754, Lyon, France.
  • Carbone A; CAS Key Laboratory of Molecular Virology and Immunology, Unit of interspecies transmission of arboviruses and antivirals, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Cosset FL; CAS Key Laboratory of Molecular Virology and Immunology, Unit of interspecies transmission of arboviruses and antivirals, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
  • Lavillette D; CIRI-International Center for Infectiology Research, Team EVIR, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Univ Lyon, Lyon, France.
PLoS Pathog ; 14(3): e1006908, 2018 03.
Article en En | MEDLINE | ID: mdl-29505618

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas del Envoltorio Viral / Hepacivirus / Evolución Molecular / Internalización del Virus Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas del Envoltorio Viral / Hepacivirus / Evolución Molecular / Internalización del Virus Límite: Animals / Humans Idioma: En Año: 2018 Tipo del documento: Article