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Report of a series of 82 cases of Buruli ulcer from Nigeria treated in Benin, from 2006 to 2016.
Ayelo, Gilbert Adjimon; Anagonou, Esai; Wadagni, Anita Carolle; Barogui, Yves Thierry; Dossou, Ange Dodji; Houezo, Jean Gabin; Aguiar, Julia; Johnson, Roch Christian; Saizonou, Raoul; Asiedu, Kingsley; Sopoh, Ghislain Emmanuel.
  • Ayelo GA; Centre de Dépistage et de Traitement de l'Ulcère de Buruli d'Allada, Ministry of Health, Allada, Bénin.
  • Anagonou E; Programme National de Lutte contre la Lèpre et l'Ulcère de Buruli, Ministry of Health, Cotonou, Bénin.
  • Wadagni AC; Programme National de Lutte contre la Lèpre et l'Ulcère de Buruli, Ministry of Health, Cotonou, Bénin.
  • Barogui YT; Centre de Dépistage et de Traitement de l'Ulcère de Buruli de Lalo, Ministry of Health, Lalo, Bénin.
  • Dossou AD; Centre de Dépistage et de Traitement de l'Ulcère de Buruli d'Allada, Ministry of Health, Allada, Bénin.
  • Houezo JG; Programme National de Lutte contre la Lèpre et l'Ulcère de Buruli, Ministry of Health, Cotonou, Bénin.
  • Aguiar J; Centre de Dépistage et de Traitement de l'Ulcère de Buruli de Zagnanado, Ministry of Health, Zagnanado, Bénin.
  • Johnson RC; Fondation Raoul Follereau, Paris, France.
  • Saizonou R; Centre Inter Facultaire de Formation et de Recherche en Environnement pour le Développement Durable, University of Abomey-Calavi, Abomey-Calavi, Bénin.
  • Asiedu K; World Health Organization, Department of Neglected Tropical Diseases, Geneva, Switzerland.
  • Sopoh GE; World Health Organization, Department of Neglected Tropical Diseases, Geneva, Switzerland.
PLoS Negl Trop Dis ; 12(3): e0006358, 2018 03.
Article en En | MEDLINE | ID: mdl-29522516
BACKGROUND: Nigeria is one of the countries endemic for Buruli ulcer (BU) in West Africa but did not have a control programme until recently. As a result, BU patients often access treatment services in neighbouring Benin where dedicated health facilities have been established to provide treatment free of charge for BU patients. This study aimed to describe the epidemiological, clinical, biological and therapeutic characteristics of cases from Nigeria treated in three of the four treatment centers in Benin. METHODOLOGY/PRINCIPAL FINDINGS: A series of 82 BU cases from Nigeria were treated in three centres in Benin during 2006-2016 and are retrospectively described. The majority of these patients came from Ogun and Lagos States which border Benin. Most of the cases were diagnosed with ulcerative lesions (80.5%) and WHO category III lesions (82.9%); 97.5% were healed after a median hospital stay of 46 days (interquartile range [IQR]: 32-176 days). CONCLUSIONS/SIGNIFICANCE: This report adds to the epidemiological understanding of BU in Nigeria in the hope that the programme will intensify efforts aimed at early case detection and treatment.
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mycobacterium ulcerans / Úlcera de Buruli Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans / Male / Middle aged País como asunto: Africa Idioma: En Año: 2018 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Mycobacterium ulcerans / Úlcera de Buruli Tipo de estudio: Diagnostic_studies / Observational_studies / Risk_factors_studies Límite: Adolescent / Adult / Child / Female / Humans / Male / Middle aged País como asunto: Africa Idioma: En Año: 2018 Tipo del documento: Article