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A 90-day OECD TG 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of the aerosol from the carbon heated tobacco product version 1.2 (CHTP1.2) compared with cigarette smoke. I. Inhalation exposure, clinical pathology and histopathology.
Phillips, Blaine W; Schlage, Walter K; Titz, Bjoern; Kogel, Ulrike; Sciuscio, Davide; Martin, Florian; Leroy, Patrice; Vuillaume, Gregory; Krishnan, Subash; Lee, Tom; Veljkovic, Emilija; Elamin, Ashraf; Merg, Celine; Ivanov, Nikolai V; Peitsch, Manuel C; Hoeng, Julia; Vanscheeuwijck, Patrick.
  • Phillips BW; PMI R&D, Philip Morris International Research Laboratories Pte. Ltd., Science Park II, Singapore.
  • Schlage WK; Biology Consultant, Max-Baermann-Str. 21, 51429, Bergisch Gladbach, Germany.
  • Titz B; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Kogel U; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Sciuscio D; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Martin F; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Leroy P; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Vuillaume G; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Krishnan S; PMI R&D, Philip Morris International Research Laboratories Pte. Ltd., Science Park II, Singapore.
  • Lee T; PMI R&D, Philip Morris International Research Laboratories Pte. Ltd., Science Park II, Singapore.
  • Veljkovic E; PMI R&D, Philip Morris International Research Laboratories Pte. Ltd., Science Park II, Singapore.
  • Elamin A; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Merg C; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Ivanov NV; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Peitsch MC; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Hoeng J; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland.
  • Vanscheeuwijck P; PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000 Neuchatel, Switzerland. Electronic address: Patrick.Vanscheeuwijck@pmi.com.
Food Chem Toxicol ; 116(Pt B): 388-413, 2018 Jun.
Article en En | MEDLINE | ID: mdl-29654848
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistema Respiratorio / Humo / Nicotiana / Carbono / Exposición por Inhalación / Aerosoles Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2018 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Sistema Respiratorio / Humo / Nicotiana / Carbono / Exposición por Inhalación / Aerosoles Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2018 Tipo del documento: Article